![]() Gagou ME, Ganesh A, Phear G, Robinson D, Petermann E, Cox A, Meuth M (2014) Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress. Kwok M, Davies N, Agathanggelou A, Smith E, Oldreive C, Petermann E, Stewart GS,Brown J, Lau A, Pratt G, Parry H, Taylor AMR, Moss P, Hillmen P, Stankovic T (2016) ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53 or ATM defective chronic lymphocytic leukemia cells. Cancer Research 78: 5767-5779.īenedict B, van Harn T, Dekker M, Hermsen S, Kucukosmanoglu A, Pieters W, Delzenne-Goette E, Dorsman JC, Petermann E, Foijer F, te Riele H (2018) Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells. Cancer Discovery 8: 537-555.īayley R, Blakemore D, Cancian L, Dumon S, Volpe G, Ward C, Almaghrabi R, Gujar J, Reeve R, Raghavan M, Higgs M, Stewart GS, Petermann E, Garcia P (2018) MYBL2 supports DNA double strand break repair in haematopoietic stem cells. Kotsantis P, Petermann E, & Boulton SJ (2018) Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place. ![]() Ronson GE, Piberger AL, Higgs MR, Olsen AL, Stewart GS, McHugh PJ, Petermann E, Lakin ND (2018) PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation. Nazeer R, Qashqari F, Albalawi A, Piberger AL, Tilotta MT, Read M, Hu S, Davis S, McCabe C, Petermann E, Turnell A (2019) Adenovirus E1B-55K targets SMARCAL1 for degradation during infection and modulates cellular DNA replication. Landsverk HB, Sandquist LE, Bay LTE, Steurer B, Campsteijn C, Landsverk OJB, Marteijn JA, Petermann E, Trinkle-Mulcahy L, Syljuåsen RG (2020) WDR82/PNUTS-PP1 prevents transcription-replication conflicts by promoting RNA Polymerase II degradation on chromatin. Biochem J 443 : 13-26īlakemore D, Vilaplana N, Almaghrabi R, Gonzalez E, Moya M, Ward C, Murphy GJ, Gambus A, Petermann E, Stewart GS, Garcia P (2021) MYBL2 and ATM suppress replication stress in pluripotent stem cells. Jones RM, Petermann E (2012) Replication fork dynamics and the DNA damage response. Jones RM, Mortusewicz O, Afzal I, Lorvellec M, Garcia P, Helleday T, Petermann E (2013) Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress. Jones RM, Kotsantis P, Stewart GS, Groth P, Petermann E (2014) BRCA2 and RAD51 promote double-strand break formation and cell death in response to Gemcitabine. Kotsantis P, Jones RM, Higgs MR, Petermann E (2015) Cancer therapy and replication stress: forks on the road to perdition. ![]() Kotsantis P, Marques Silva L, Irmscher S, Jones RM, Folkes L, Gromak N, Petermann E (2016) Increased global transcription activity as a mechanism of replication stress in cancer. Nature Communications 11: 5863īowry A, Piberger AL, Rojas P, Saponaro M, Petermann E (2018) BET inhibition induces HEXIM1- and RAD51-dependent conflicts between transcription and replication. Piberger AL, Bowry A, Kelly RDW, Walker AK, González-Acosta D, Bailey LJ, Doherty AJ, Méndez J, Morris JR, Bryant HE, Petermann E (2020) PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts. Nature Reviews Molecular Cell Biology 8 :521-540īowry A, Kelly RDW, Petermann E (2021) Hypertranscription and replication stress in cancer. Petermann E, Lan L, Zou L (2022) Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids. ![]() Petermann E (2022) Conflicts with transcription make early replication late. ![]()
0 Comments
Leave a Reply. |